Ongoing research projects:

1. Low-cost oral mobile cancer screening for low resource setting (NIH Project in collaboration with University of Arizona)   
2. Evaluation of autofluorescence image guided surveillance of oral potentially malignant disorders and development of prediction model for risk assessment in malignant transformation: A longitudinal observational study.
3. Assessment of Artificial Neural Network classifier on oral potentially malignant disorders and oral cancer in a real-world settings-A prospective study.
4. “Screen and Treat” – Oral Cancer Control program – A scale up approach

Completed research projects-

1. A low-cost simple oral cancer screening device for low-resource setting (NIH-DBT)   
2. Clinical study of ‘Cellscope’ as a tele microscopy tool for oral cancer screening (in collaboration with Siemens Technology and University of California, Berkeley) 
3. Observation of oral premalignant and malignant lesions using exogenous fluorophores and handheld fluorescent imaging (in collaboration with University of Minnesota) 
4. Ex-vivo molecular imaging of oral potentially malignant and malignant lesion using PARPi-Fl. 
5. Low-cost, portable and contemporaneous optical imaging technology in oral cancer diagnosis (in collaboration with Memorial Sloan Kettering Cancer Centre)

Patent filed: Molecular Marker based oral cytology for detection of potentially malignant and malignant oral lesions

Research grants received: 

• Grant from National Institutes of Health, USA for project titled ‘Low-cost mobile oral cancer screening for low resource settings’ for the duration 2016-22.
• Grant from RGUHS for project titled ‘Implant location made simple: a novel technique using radiographic object localization’ during 2019.

Capacity building initiatives undertaken by the department

1. A “Master training program” for 38 medical officers from different districts of Karnataka, who were District Coordinators and Tobacco Cessation Counsellors were trained for early oral cancer detection in association with state tobacco control cell and Non-Communicable Diseases Cell, Department of Health and Family welfare, Government of Karnataka & Biocon Foundation. 

2. Training of Frontline healthcare providers (ASHAs, General dentists, Interns, medical and paramedics) for early detection of oral cancer.
3. Online training module developed for early detection of oral cancer for interns and final year students.

Selected publications in international and national peer-reviewed indexed journals:

1. Bonney Lee James, Sumsum P Sunny, Andrew Emon Heidari, Ravindra D
   Ramanjinappa, Tracie Lam, Anne V Tran, Sandeep K, Shiladitya Sil, Vidya
   Tiwari, Sanjana Patrick, Vijay Pillai, Vivek Shetty, Naveen Hedne, Darshat
   Shah, Nameeta Shah, Zhongping Chen, Uma K, Subhashini A R, Shubha G, Praveen
   Birur, Petra Wilder Smith, Amritha Suresh, Moni Abraham Kuriakose. Validation of a point-of-care Optical Coherence Tomography device with
   machine learning algorithm for detection of oral potentially malignant and
   malignant lesions. Cancers 2021
2. Bofan Song, Sumsum Sunny, Shaobai Li, Keerthi Gurushanth, Pramila Mendonca, Nirza Mukhia, Sanjana Patrick, Shubha Gurudath, Subhashini Raghavan, Tsusennaro Imchen, Shirley T. Leivon, Trupti Kolur, Vivek Shetty, Vidya Bushan, Rohan Ramesh, Natzem Lima, Vijay Pillai, Petra Wilder-Smith, Alben Sigamani, Amritha Suresh, Moni A. Kuriakose, Praveen Birur, Rongguang Liang, "Mobile-based oral cancer classification for point-of-care screening," J. Biomed. Opt. 26(6) 065003 (23 June 2021) https://doi.org/10.1117/1.JBO.26.6.065003
3. Thankappan K, Praveen Birur, Raj M, Djalalov S, Subramanian S, Iyer S,  Kuriakose MA. Oral cancer screening using mobile phone-based(mHealth) approach versus conventional oral examination approach, protocol of a cluster randomized study with cost-effectiveness analysis. Internat J of Surg Protoc 2020;23:1-5. https://doi.org/10.1016/j.isjp.2020.07.001.
4. Sarode CS, Sarode GS, Birur P, Alhazmi YA, Patil S. Keratinocyte dissociation (desmolysis/acantholysis) in ameloblastoma. Clinics and Practice 2020; 10:1255.
5. Kossatz, S., Pirovano, G., Demétrio De Souza França, P. Arianna L. Strome1 , Sunny PS, Zanoni DK, Mauguen A, Carney B, Brand C, Shah  V, Ramanajinappa RD ,Hedne N, Birur  P, Sihag S, Ghossein RA, Gönen M, Strome M, Suresh A, Molena D, Ganly I, Kuriakose MA, Patel SG, and Reiner T. Validation of the use of a fluorescent PARP1 inhibitor for the detection of oral, oropharyngeal and oesophageal epithelial cancers. Nat Biomed Eng 4, 272–285 (2020). https://doi.org/10.1038/s41551-020-0526-9
6. Prabhash K, Babu G, Chaturvedi P, Kuriakose M, Birur P, Anand AK, et al. Indian clinical practice consensus guidelines for the management of very advanced disease of squamous cell carcinoma of head and neck. Indian J Cancer 2020;57:S22-5.
7. Singhal M, Prabhash K, Babu G, Chaturvedi P, Kuriakose M, Birur P, et al. Indian clinical practice consensus guidelines for the management of laryngeal cancer. Indian J Cancer 2020;57:S19-21.
8. Babu G, Prabhash K, Chaturvedi P, Kuriakose M, Birur P, Anand AK, et al. Indian clinical practice consensus guidelines for the management of hypopharyngeal cancer. Indian J Cancer 2020;57:S16-8.
9. Prabhash K, Babu G, Chaturvedi P, Kuriakose M, Birur P, Anand AK, et al. Indian clinical practice consensus guidelines for the management of oropharyngeal cancer. Indian J Cancer 2020;57:S12-5. 
10. Gairola M, Prabhash K, Babu G, Chaturvedi P, Kuriakose M, Birur P, et al. Indian clinical practice consensus guidelines for the management of nasopharyngeal cancer. Indian J Cancer 2020;57:S9-11.
11. Chaturvedi P, Prabhash K, Babu G, Kuriakose M, Birur P, Anand AK, et al. Indian clinical practice consensus guidelines for the management of oral cavity cancer. Indian J Cancer 2020;57:S6-8.
12. Prabhash K, Babu G, Chaturvedi P, Kuriakose M, Birur P,Anand AK, et al. Indian clinical practice consensus guidelines for the management of squamous cell carcinoma of head and neck. Indian J Cancer 2020;57:S1-5.
13. Sunny S, Baby A, James BL, Balaji D, N. V. A, Rana MH, Gurpur P, Skandarajah A, Michael D’Ambrosio, Ravindra Doddathimmasandra Ramanjinappa, Sunil Paramel Mohan,  Nisheena Raghavan, Uma Kandasarma,  Sangeetha N, Subhasini Raghavan, Naveen Hedne, Felix Koch, Daniel A. Fletcher, Sumithra Selvam, Manohar Kollega, Praveen Birur N, Lance Ladic, Amritha Suresh, Hardik J. Pandya, Moni Abraham Kuriakose.  A smart tele-cytology point-of-care platform for oral cancer screening. PLoS ONE 2019;14(11): e0224885. https://doi.org/ 10.1371/journal.pone.0224885.
14. Johnson A, Baeten J, Patel K, Killian M, Sunny S, Suresh A, Uma . K, Birur P, Kuriakose M, Kademani D. Evaluation of a Lectin-Based Imaging System for the Chairside Detection of Oral Dysplasia and Malignancy. Journal of Oral and Maxillofacial Surgery  2019:1941-52. doi: https://doi.org/10.1016/j.joms.2019.03.012
15. Ross D. Uthoff, Bofan Song, Sumsum Sunny, Sanjana Patrick, Amritha Suresh, Trupti Kolur, Keerthi Gurushanth, Kimberly Wooten, Vishal Gupta, Mary E. Platek, Anurag K. Singh, Petra Wilder-Smith, Moni Abraham Kuriakose, Praveen Birur, Rongguang Liang. “Small form factor, flexible, dual-modality handheld probe for smartphone-based, point-of-care oral and oropharyngeal cancer screening,” J. Biomed. Opt 2019;24(10):106003, doi: 10.1117/1.JBO.24.10.106003.
16. A. E. Heidari et al., "Optical Coherence Tomography as an Oral Cancer Screening Adjunct in a Low Resource Settings," in IEEE Journal of Selected Topics in Quantum Electronics 2019;25:1-8. 
17. Birur NP, Gurushanth K, Patrick S, Sunny SP, Raghavan SA, Gurudath S, Hegde U, Tiwari V, Jain V, Imran M, Rao P, Kuriakose MA. Role of community health worker in a mobile health program for early detection of oral cancer. Indian J Cancer 2019;56:107-13.
18. Ross D. Uthoff, Bofan Song, Sumsum Sunny, Sanjana Patrick, Amritha Suresh, Trupti Kolur, G. Keerthi, Oliver Spires1, Afarin Anbarani, Petra Wilder-Smith, Moni Abraham Kuriakose, Praveen Birur, Rongguang Liang. Point-of-care, smartphone-based, dual-modality, dual-view, oral cancer screening device with neural network classification for low-resource communities. PLoS ONE 2018; 13(12): e0207493. https://doi.org/10.1371/journal.pone.0207493
19. Ross D. Utho, Bofan Song, Praveen Birur, Moni Abraham Kuriakose, Sumsum Sunny, Amritha Suresh, Sanjana Patrick, Afarin Anbarani, Oliver Spires, Petra Wilder-Smith,  Rongguang Liang. Development of a dual-modality, dual-view smartphone-based imaging system for oral cancer detection. Proc SPIE 2018; 104860V: doi: 10.1117/12.2296435.
20. Birur NP, Patrick S, Bajaj S, Raghavan S, Suresh A, Sunny SP, Chigurupati R, Wilder-Smith P, Gurushanth K, Gurudath S, Rao P, Kuriakose MA. A Novel Mobile Health Approach to Early Diagnosis of Oral Cancer. J Contemp Dent Pract 2018;19(9):1-7.
21. Bofan Song, Sumsum Sunny, Ross D. Uthoff, Sanjana Patrick, Amritha Suresh, Trupti Kolur, G. Keerthi, Afarin Anbarani, Petra Wilder-Smith, Moni Abraham Kuriakose, Praveen Birur, Jeffrey J. Rodriguez, And Rongguang Liang.  Automatic classification of dual-modalilty, smartphone-based oral dysplasia and malignancy images using deep learning. Biomed Opt Express 2018;11(9):1-12.
22. Shubhasini A Raghavan, Praveen Birur, Usha Hegde, Uma K, Shubha Gurudath, Keerthi G, Shiladitya Sil. Inter and intraobserver variability in diagnosis of dysplasia in Oral Potentially Malignant Disorders. Asian Pac J Cancer Prev 2017;18 (12): 3251-3254.
23. Nayak DS, Raghavan SA, Birur P, Gurudath S, Keerthi G. Determination of Proximity of Mandibular Third Molar to Mandibular Canal Using Panoramic Radiography and Cone-beam Computed Tomography. J Indian Acad Oral Med Radiol 2017;29:273-7.
24. Patrick S, Birur NP, Gurushanth K, Raghavan AS, Gurudath S. Comparison of gray values of cone-beam computed tomography with Hounsfield units of Multislice computed tomography: An in vitro study. Indian J Dent Res 2017;28:66-70.
25. John Baeten, Alexander Johnson, Sumsum Sunny, Amritha Suresh, Praveen Birur, Uma K,  Deepak Kademani. Chairside molecular imaging of aberrant glycosylation in subjects with suspicious oral lesions using fluorescently labelled wheat germ agglutinin. Head & Neck. 2017;1–10.
26. Subin Surendran, Gangotri Siddappa, Amrutha Mohan, WesleyHicksJr., Vijayvel Jayaprakash, Christina Mimikos, Mohammed Mahri, Fatima Almarzouki, Kayla Morrell, Ravindra Ravi, Sindhu Govindan, C.N.Sushma, Nisheena Raghavan, Praveen Birur, JeyaramIlayaraja, Mihai Merzianu, MaryReid, Amritha Suresh, Moni Abraham Kuriakose. Cancer stem cell and its niche in malignant progression of oral potentially malignant disorders. Oral Oncology 2017;75:140-147.
27. Arunan Skandarajah, Sumsum P. Sunny, Praveen Gurpur, Clay D. Reber, Michael V. D'Ambrosio, Nisheena Raghavan, Bonney Lee James, Ravindra D. Ramanjinappa, Amritha Suresh, Uma Kandasarma, Praveen Birur, Vinay V. Kumar, Honorius- Cezar Galmeanu, Alexandru Mihail Itu, Mihai Modiga-Arsu, Saskia Rausch, Maria Sramek, Manohar Kollegal, Gianluca Paladini, Moni Kuriakose, Lance Ladic, Felix Koch, Daniel Fletcher. Mobile microscopy as a screening tool for oral cancer in India: A pilot study. PLoS ONE 2017;12(11): e0188440. https://doi.org/10.1371/journal.pone.0188440.
28. Pekka EH, Joonas JS, Eija M, Diti D, Timo T, Satu AT, Paul M, Chetan M, Rani D, Praveen B. A low resource setting oral lesion-screening tool. Medical biochemistry, Science matters 2016:1-11.
29. Birur PN, Sunny SP, Jena S, K Uma, Raghavan SA, Bhanushree R, Sunitha PS, Patrick S, Kuriakose R, Malliah J, Suresh A, Chigurupati R, Desai R, Kuriakose MA. Mobile health application for remote oral cancer surveillance. J Am Dent Assoc 2015;146(12):886-894.
30. Rani Desai, Praveen Birur, Suchitra Bajaj, Shubhasini AR, Bhanushree R, Shubha G, Keerthi G, Vidya Tiwari, Sanjana Patrick, Usha Hedge, Sujit Shetty, Vidya Nagabhushan, Sandeep Kankanala, Shreyas Shah. Smokeless tobacco associated lesions: A mobile health approach. The J of Contem Dent Prac 2015;16(10): 813-818.
31. Suneeta Krishnan, Preet K. Dhillon, Afsan Bhadelia, Anna Schurmann, Partha Basu, Neerja Bhatla, Praveen Birur, Rajeev Colaco, Subhojit Dey, Surbhi Grover, Harmala Gupta, Rakesh Gupta, Vandana Gupta, Megan A. Lewis, Ravi Mehrotra, Ann McMikel, Arnab Mukherji, Navami Naik, Laura Nyblade, Sanghamitra Pati1, Radhakrishna Pillai, Preetha Rajaraman, Chalurvarayaswamy Ramesh, G. K. Rath, Richard Reithinger, Rengaswamy Sankaranarayanan, Jerard Selvam, M. S., Shanmugam, Krithiga Shridhar, Maqsood Siddiqi, Linda Squiers, Sujha Subramanian, Sandra M. Travasso, Yogesh Verma, M. Vijayakumar, Bryan J. Weiner, K. Srinath Reddy, Felicia M. Knau. Report from a symposium on catalyzing primary and secondary prevention of cancer in India. Cancer Causes Control 2015;26:1671–1684
32. Raghavan SA, Puttaswamiah RN, Birur PN, Ramaswamy B, Sunny SP. Antidepressant-induced burning mouth syndrome- a unique case. Korean J Pain July 2014; 27(3): 294-296.
33. Praveen BN, Shubhasini AR, Bhanushree R, Sumsum PS, Sushma CN. Radiation in Dental Practice- Awareness, Protection and Recommendations’ Journal of Contemporary Dental Practice 2013;14(1):143-148.

Chapters in textbooks:

1. Praveen Birur and R Ongole: Authors of Textbook of Oral Medicine and Radiology, 1^st and 2^nd editions. Published by Elsevier
2. Shubhasini A R: Contributed chapters to textbook of Oral Medicine and Radiology, Praveen Birur and R Ongole
3. Keerthi G: Contributed chapters to Textbook of Oral medicine and Radiology